Little Known Facts About cees dekker.
Little Known Facts About cees dekker.
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‘Sure, that may be about correct. I seek for a physical comprehension of Organic techniques within a base-up way. I think you might distinguish a few lines of investigation in my team for the time being. The 1st concerns chromosome construction: How would you receive a metre-lengthy DNA polymer folded and organised in this type of microscopic mobile? Now we have designed visualisation approaches that make it possible for us to review how, by way of example, SMC proteins loop DNA (video clip on Youtube) to be able to build up chromosomes.
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Nanofabrication of electrodes with sub-five nm spacing for transport experiments on single molecules and metallic clusters
We produce position-of-care diagnostics test of neglected tropical health conditions within just source-restricted configurations, based upon Crspr/Cas9 detecting of pathogen’s DNA in human body fluids.
From the several years pursuing these discoveries, my investigation passions shifted to biophysics and nanobiology, and I turned fewer involved with the development of nanotube electronics. The focus of numerous scientists in the field also shifted to graphene (exactly where, funnily enough, the main graphene ribbons ended up referred to as ‘nanotubes which are cut open up alongside their duration’) immediately after the invention of the two-dimensional material in 2004.
We form germs into forms that deviate from their natural phenotype. Specifically, I'll exhibit our capacity to form live E. coli bacteria into novel styles for example rectangles, squares, triangles and circles.
Atomic drive microscopy exhibits that vaccinia topoisomerase IB generates filaments on DNA in the cooperative fashion
In 1993, as a young and eager affiliate professor at Delft College of Engineering, I'd in the beginning focused the investigation endeavours of my group on measuring the electrical conductance of just one conducting-polymer molecule. Within just two years, we had developed a tool wherein a single wire of a phthalocyaninepolysiloxane polymer was linked involving two intently spaced metal nanoelectrodes.
But carbon nanotubes have remained a investigate subject matter of sizeable desire to quite a few. In fact, the outlook on working with carbon nanotubes to develop functional products, in parts for instance radio-frequency electronics, electronic electronics and flexible electronics, remains dazzling.
FtsZ treadmilling is important for Z-ring condensation and septal constriction initiation in bacterial mobile division
2006, very first demonstration of molecular sorting inside of a lab on a chip making use of biomotors; discovery of nanobubbles in good-state nanopores; and very first estimate of electrokinetic Electricity conversion in a nanofluidic channel
2008, to start with observation of protein-coated DNA translocation through nanopores; fixed the origin ceesdekker of the electrophoretic drive on DNA in nanopores; found out an important velocity maximize of microtubules in electric powered fields; found out an anomalous electro-hydrodynamic orientation of microtubules; and solved the origin of sound in carbon nanotubes in liquid
2004, discovery of new physics in translocation of DNA as a result of nanopores; 1st experimental research of ions conduction in nanofluidic channels; first electrochemistry with unique solitary-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; 1st electrical docking of microtubules on kinesin-coated nanostructures; 1st biophysics characterization from the mechanical Attributes of double-stranded RNA; and 1st single-molecule review of DNA translocation by a restriction-modification enzyme.